School of Medicine

Wayne State University School of Medicine

Whole Genome Amplification

General Information

Whole Genome Amplification (WGA) techniques have become a valuable tool for the genomics research community.  With the ability to vastly increase the quantity of genomic DNA, WGA gives investigators the opportunity to obtain valuable genetic information from even the most limited of sample types. Two of the most prominent methods available are Multiple Displacement Amplification (MDA), a strand displacement-based methodology, and OmniPlex™ Technology, a random fragmentation-based methodology. Both have a variety of commercial kits available for specific sample types and desired DNA yield.  For more information, please click here.

The Applied Genomics Technology Center (AGTC) has validated the Qiagen REPLI-g® Midi Kit, a Multiple Displacement Amplification (MDA) method.

Sample Submission

Please contact Nicole Ducharme prior to collecting and submitting samples for whole genome amplification.  This way we can determine if your particular sample set is compatible with our validated method.  If deemed compatible, sample drop off will be authorized and coordinated.