- The AGTC will be closed on Thursday, November 26, and Friday, November 27, for the Thanksgiving Holiday
- We just received our new epMotion ™ 5075 LH
- The Eppendorf ® epMotion ™ 5075 LH Workstation is a benchtop liquid handling system. During the next...
- Looking to expand our Current Services
- We are always looking to expand our current services. Please contact Sue Land to discuss any current or...
- WSU School of Medicine News
Announcements
Bock CH, Schwartz AG, Ruterbusch JJ, Levin AM, Neslund-Dudas C, Land SJ, Wenzlaff AS, Reich D, McKeigue P, Chen W, Heath EI, Powell IJ, Kittles RA, Rybicki BA. Results from a prostate cancer admixture mapping study in African-American-American men. Hum Genet, 2009 (in press)
Cote ML, Yoo W, Wenzlaff AS, Prysak GM, Santer SK, Claeys GB, Van Dyke AL, Land SJ, Schwartz AG. Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women. Carcinogenesis 30(4):626-635, 2009.
Deshmukh A, Rodrigue KM, Kennedy KM, Land S, Jacobs BS, Raz N. Synergistic effects of the MTHFR C677T polymorphism and hypertension on spatial navigation. Biol. Psychol. 80(2):240-245, 2009.
Kato I, Cichon M, Yee CL, Land S, Korczak, J. African American-preponderant single nucleotide polymorphisms (SNP) and risk of breast cancer. Cancer Epidemiology 33: 24-30, 2009.
Kennedy KM, Rodrigue KM, Land SJ, Raz N. BDNF val166met polymorphism influences age differences in micorstructure of the corpus callosum. Frontiers in Human Neurosciences, 2009 (in press)
Lisak RP, Benjamins JA, Bealmear B, Nedelkoska L, Studzinski D, Retland E., Yao B, Land S. Differential Effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures. J of Neuroinflammation 6:4, 2009.
Platts, AE, Land SJ, Chen L, Page GP, Rasouli P, Wang L, Lu X, and Ruden DM. Massively parallel resequencing of the isogenic Drosophila melanogaster strain W1118; iso-2; iso-3 identifies hotspots for mutations in sensory perception genes. Fly, 2009 (in press).
Raz N, Dahle CL, Rodrigue KM, Kennedy KM, Land S. Effects of age, genes, and pulse pressure on excutive functions in healthy adults. Neurobiol. Aging, 2009 (in press).
Raz N, Rodrigue KM, Kennedy KM, Land S. Genetic and vascular modifiers of age-sensitive cognitive skills: effects of COMT, BDNF, ApoE, and hypertension. Neuropsychology 23(1): 105-116, 2009.
Van Dyke AL, Cote ML, Wenzlaff AS, Land S, Schwartz AG. Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies. Cytokine 46(2): 236-244, 2009.
Van Dyke AL, Cote ML, Wenzlaff AS, Chen W, Abrams J, Land S, Giroux CN, Schwartz AG. Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women. Cancer Epidemiol Biomarkers Prev 18(6): 1829-1840, 2009.
Balan, V. (2008). "Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study". Cancer research (Baltimore) (0008-5472), 68 (24), p. 10045.
Barnholtz-Sloan J, Sloan AE, Land S, Kupsky W, and Monteiro AN. Somatic Alterations in Brain Tumors. Human Mutations,Oncol. Rep. 20:203-210, 2008.
Fridman, A L (2008). "Critical pathways in cellular senescence and immortalization revealed by gene expression profiling". Oncogene (0950-9232), 27 (46), p. 5975.
Haddad, R (2008). "Angiogenesis gene expression in mouse uterus during the common pathway of parturition." American journal of obstetrics and gynecology (0002-9378), 198 (5), p. 539e1.
Kocarek, T (2008). "Age- and sex-dependent expression of multiple murine hepatic hydroxysteroid sulfotransferase (SULT2A) genes". Biochemical pharmacology (0006-2952), 76 (8), p. 1036.
Li, Q. (2008). "Interferon Regulatory Factors IRF5 and IRF7 Inhibit Growth and Induce Senescence in Immortal Li-Fraumeni Fibroblasts". Molecular cancer research (1541-7786), 6 (5), p. 770.
Raz N, Dahle CL, Rodrigue KM, Kennedy KM, Land SJ, Jacobs BS. Brain-derived neurotrophic factor Val66Met and blood glucose: a synergistic effect on memory. Frontiers in Human Neurosciences 2 :1-6, 2008.
Rose, W. E. (2008). "Daptomycin Activity against Staphylococcus aureus following Vancomycin Exposure in an In Vitro Pharmacodynamic Model with Simulated Endocardial Vegetations". Antimicrobial agents and chemotherapy (0066-4804), 52 (3), p. 831.
Thakur, Archana A (2008). "Gene expression profiles in primary pancreatic tumors and metastatic lesions of Ela-c-myc transgenic mice". Molecular cancer (1476-4598), 7 (1), p. 11.
Than, Nandor Gabor (2008)."Chorioamnionitis and Increased Galectin-1 Expression in PPROM - An Anti-Inflammatory Response in the Fetal Membranes?". American journal of reproductive immunology (1989) (1046-7408), 60 (4), p. 298.
Than, N. G. (2008). "Emergence of hormonal and redox regulation of galectin-1 in placental mammals: Implication in maternal-fetal immune tolerance". Proceedings of the National Academy of Sciences of the United States of America (0027-8424), 105 (41), p. 15819.
Toft, J. H. (2008). “Whole-genome microarray and targeted analysis of angiogenesis-regulating gene expression (ENG, FLT1, VEGF, PlGF) in placentasfrom pre-eclamptic and small-for-gestational-age pregnancies”. The Journal of Maternal-Fetal and Neonatal Medicine, April 2008; 21(4): 267–273
Yu, Y. J. (2008). "Exfoliated Cells in Stool: A Source for Reverse Transcription-PCR-Based Analysis of Biomarkers of Gastrointestinal Cancer". Cancer epidemiology, biomarkers & prevention (1055-9965), 17 (2), p. 455.
Cote ML, Wenzlaff AS, Bock CH, Land SJ, Santer SK, Schwartz DR, Schwartz AG. Combinations of cytochrome P-450 genotypes and risk of early-onset lung cancer in Caucasians and African Americans: A population-based study. Lung Cancer 55(3): 255-262, 2007.
DeMarco, C. E. (2007). "Efflux-Related Resistance to Norfloxacin, Dyes, and Biocides in Bloodstream Isolates of Staphylococcus aureus". Antimicrobial agents and chemotherapy (0066-4804), 51 (9), p. 3235.
Fang, H.-L. (2007). "Positive and Negative Regulation of Human Hepatic Hydroxysteroid Sulfotransferase (SULT2A1) Gene Transcription by Rifampicin: Roles of Hepatocyte Nuclear Factor 4 and Pregnane X Receptor". The Journal of pharmacology and experimental therapeutics (0022-3565), 323 (2), p. 586.
LaPlante, K. L. (2007). "Fluoroquinolone Resistance in Streptococcus pneumoniae: Area Under the Concentration-Time Curve/MIC Ratio and Resistance Development with Gatifloxacin, Gemifloxacin, Levofloxacin, and Moxifloxacin". Antimicrobial agents and chemotherapy (0066-4804), 51 (4), p. 1315.
Lenk, Guy M (2007). "Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms". BMC genomics (1471-2164), 8 (1), p. 237.
Lisak, Robert P (2007). "Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for glial and neural-related molecules in central nervous system mixed glial cell cultures: neurotrophins, growth factors and structural proteins". Journal of neuroinflammation (1742-2094), 4 (1), p. 30.
Streicher, K L (2007). "Transforming function of the LSM1 oncogene in human breast cancers with the 8p11–12 amplicon". Oncogene (0950-9232), 26 (14), p. 2104.
Wang, Y. (2007). "Synergistic Effect of Cyclin D1 and c-Myc Leads to More Aggressive and Invasive Mammary Tumors in Severe Combined Immunodeficient Mice". Cancer research (Baltimore) (0008-5472), 67 (8), p. 3698.
Weinsheimer, S. (2007). "Association of Kallikrein Gene Polymorphisms With Intracranial Aneurysms". Stroke (1970) (0039-2499), 38 (10), p. 2670.
Weinsheimer S, Goodard KA, Parrado AR, Lu Q, Sinha M, Lebedeva ER, Ronkainen A, Niemela M, Khusnutdinova EK, Khusainova RI, Helin K, Jaaskelainen JE, Sakovich VP, Land S, Kuivaniemi H, Tromp G. Association of kallikrein gene polymorphisms with intracranial aneurysms in the Finnish and Russian populations. Stroke, 38:2670-2676, 2007.
Weinsheimer S, Lenk GM, Van der Voet M, Land S, Ronkainen A, Alafuzoff I, Kuivaniemi H, Tromp G. Integration of expression profiles and genetic mapping data to identify candidate genes in intracranial aneurysm. American Physiological Society 32:45-57, 2007.
Chowdhury, Mahboob A (2006)."Identification of novel functional sequence variants in the gene for peptidase inhibitor 3". BMC medical genetics (1471-2350), 7 (1), p. 49.
Fridman AL, Tang L, Kulaeva Ol, Ye B, Li Q, Nahhas F, Roberts PC, Land SJ, Abrams J, Tainsky MA. Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle and cytoskeleton. Journal of Gerontology: Biological Sciences 61A(9):879-889,2006.
Haddad, R (2006). "Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature." American journal of obstetrics and gynecology (0002-9378), 195 (2), p. 394e1.
Haddad, R (2006). "Uterine transcriptomes of bacteria-induced and ovariectomy-induced preterm labor in mice are characterized by differential expression of arachidonate metabolism genes". American journal of obstetrics and gynecology (0002-9378), 195 (3), p. 822.
Hassan, S (2006). "The transcriptome of the uterine cervix before and after spontaneous term parturition". American journal of obstetrics and gynecology (0002-9378), 195 (3), p. 778.
Lisak RP, Benjamins JA, Bealmear B, Yao B, Land S, Nedelkoska L, Skundric D. Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for immune-related molecules by central nervous system mixed glial cell cultures. Multiple Sclerosis 12:149-168, 2006.
Liu, Z (2006). "Tracking down the “head blob”: Comparative analysis of wingless expression in the developing insect procephalon reveals progressive reduction of embryonic visual system patterning in higher insects". Arthropod structure & development (1467-8039), 35 (4), p. 341.
Messersmith, DJ (2006)."A Web-based assessment of bioinformatics end-user support services at US universities". Journal of the Medical Library Association (1536-5050), 94 (3), p. 299.
Miller, J (2006). "Gene expression analysis of the development of congenital hydrocephalus in the H-Tx rat". Brain research (0006-8993), 1075 (1), p. 36.
Santra, M. (2006). "Ectopic Doublecortin Gene Expression Suppresses the Malignant Phenotype in Glioblastoma Cells". Cancer research (Baltimore) (0008-5472), 66 (24), p. 11726.
Santra, M (2006). "Ectopic expression of doublecortin protects adult rat progenitor cells and human glioma cells from severe oxygen and glucose deprivation". Neuroscience (0306-4522), 142 (3), p. 739.
Wendell, D (2006). "Global analysis of gene expression in the estrogen induced pituitary tumor of the F344 rat". The Journal of steroid biochemistry and molecular biology (0960-0760), 101 (4-5), p. 188.
Bock CH, Wenzlaff AS, Cote ML, Land SJ, Schwartz AG. NQO1 T allele associated with decreased risk of later age at diagnosis lung cancer among never smokers: results from a population-based study. Carcinogenesis 26: 381-386,2005.
Cote M, Kardia SL, Wenzlaff AS, Land SJ, Schwartz AG. Combinations of glutathione S-transferase polymorphisms and risk of early-onset lung cancer in Caucasian and African American populations. Carcinogenesis 26(4): 811-819, 2005.
Dong, Ying (2005)."Comparative analysis of Wingless patterning in the embryonic grasshopper eye". Development genes and evolution (0949-944X), 215 (4), p. 177.
Dong, Ying Y (2005)."Nymphal RNAi: systemic RNAi mediated gene knockdown in juvenile grasshopper". BMC biotechnology (1472-6750), 5 (1), p. 25.
Fang, H.-L. (2005). "Regulation of Human Hepatic Hydroxysteroid Sulfotransferase Gene Expression by the Peroxisome Proliferator-Activated Receptor Transcription Factor". Molecular pharmacology (0026-895X), 67 (4), p. 1257.
Kaplan J, Land S. Influence of maternal-fetal histocompatibility and MHC zygosity on maternal microchimerism. J. Immunol. 174 (11): 7123-7128, 2005.
Ogata, Toru (2005). "Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms". Journal of vascular surgery (0741-5214), 41 (6), p. 1036.
Platts, Adrian E. (2005). "LARaLink 2.0: A Comprehensive Aid to Basic and Clinical Cytogenetic Research". Genetic testing (1090-6576), 9 (4), p. 334.
Powell IJ, Land SJ, Dey J, Heilbrun LK, Hughes MR, Sakr W, Everson RB. Impact of CAG repeats in exon 1 of the androgen receptor on progression after prostatectomy. Cancer 103(3), 528-537, 2005.
Thakur, Archana (2005)."The role of X-linked genes in breast cancer". Breast cancer research and treatment (0167-6806), 93 (2), p. 135.
Wenzlaff AS, Cote ML, Bock CH, Land SJ, Santer SK, Schwartz DR, Schwartz AG. CYP1A1 and CYP1B1 and risk of lung cancer among never smokers: a population-based study. Carcinogenesis 26(12): 2207-2212, 2005.
Wenzlaff AS, Cote ML, Bock CH, Land SJ, Schwartz AG. GSTM1, GSTT1 and GSTP1 polymorphisms, environmental tobacco smoke exposure and risk of lung cancer among never smokers: a population-based study. Carcinogenesis 26: 395-401, 2005.
Albertson, Dawn N. (2004). "Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin". Journal of neurochemistry (0022-3042), 88 (5), p. 1211.
Berry S, Hassan S, Russell E, Kukuruga D, Land S, Kaplan J. Association of maternal histocompatibility at class II HLA loci with maternal microchimerism in the fetus. Pediatr Res. 56(1):73-8, 2004.
Liu, D., Yao, B., Fayz, B., Womble, D., and Krawetz, S. (2004) Comparative Evaluation of Microarray Analysis Software. Molecular Biotechnology. pp 225-232.
Martins RP, Ostermeier GC, Krawetz SA. (2004) Nuclear matrix interactions at the human protamine domain: A working model of potentiation. J Biol Chem. 2004 Sep 27.
Ostermeier GC, Miller D, Huntriss JD, Diamond MP, Krawetz SA. (2004) Reproductive biology: delivering spermatozoan RNA to the oocyte. Nature. 2004 May 13;429(6988):154.
Pass HI, Liu Z, Wali A, Bueno R, Land S, Lott D, Siddiq F, Lonardo F, Carbone M, Draghici S. (2004) Gene expression profiles predict survival and progression of pleural mesothelioma. Clin Cancer Res. 2004 Feb 1;10(3):849-59.
Thomas, DM (2004). "Identification of differentially regulated transcripts in mouse striatum following methamphetamine treatment-an oligonucleotide microarray approach". Journal of Neurochemistry (0022-3042), 88 (2), p. 380.
Williams H, Powell IJ, Land SJ, Sakr WA, Hughes MR, Patel NP, Heilbrun LK, Everson RB. (2004) Vitamin D receptor gene polymorphisms and disease free survival after radical prostatectomy. Prostate. 2004 Nov 1;61(3):267.
Yao B, Rakhade SN, Li Q, Ahmed S, Krauss R, Draghici S, Loeb JA. Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells. BMC Bioinformatics. 2004 Jul 23;5(1):99.
Yoo G, Nguyen N, Du W, Schwartz A, Land S, Lin H, Kewson D, Murphy L, Cilluffo D, Ensley J, Tainsky M. Microsatellite Alterations in African Americans with Head and Neck Cancer. The Laryngoscope 114, 1619-1624, 2004.
Krawetz, S.A., and Womble, D.D., eds. (2003) Introduction to Bioinformatics: A Theoretical and Practical Approach (Totowa, New Jersey: Humana Press, Inc.).
Kulaeva OI, Draghici S, Tang L, Kraniak JM, Land SJ, Tainsky MA. Epigenetic silencing of multiple interferon pathway genes after cellular immortalization. Oncogene 22:4118-4127, 2003.
Ramos-Nino ME, Scapoli L, Martinelli M, Land S, Mossman B. Microarray analysis and RNA silencing link fra-1 to cd44 and c-met expression in mesothelioma. Cancer Res. 63(13):3539-3545, 2003.
Krawetz, S.K., and Womble, D.D. (2001). "Design and Implementation of an Introductory Course for Computer Applications in Molecular Genetics: A Case Study." In Proceedings of the Atlantic Symposium on Computational Biology and Genome Information Systems & Technology. C.H. Wu, P.P. Wang, and J.T.L. Wang, eds. (Association for Intelligent Machinery, Inc.), pp. 230-234.

